Nimbatiktam for The treatment of Psoriasis

The Central Council for Ayurveda & Siddha, under Ministry of Health & Family Welfare has developed the technology for above preparation.

Psoriasis is a chronic, recurrent papulo-squamous dermatosis with silvery grey scaling papules of plaques.  It is a commonly occurring condition and constitutes 2-4 percent of all cases of skin diseases One of the active principles Nimbidin isolated from the oil of azadirachta  azadirachta indica Linn (Nimba), a common drug widely used in various types of skin diseases in Ayurveda.  A bitter solid isolate (nimbatiktam) was studied clinically on diagnosed cases of psoriasis.  The drug was administered in capsule form twice a day for 60 days.  Lajjaalu keram applied externally (Mimosa pudica) There was significant improvement in symptoms like roughness, exfoliation etc.  about 87% of the patients got relieved from all these symptoms

CLINICAL TRIALS

362 Patient   with well-defined psoriatic lesions with no complications was taken for clinical trial. 60 % cases showed  good control without any relapse. A daily intake of about 2400 calories containing of non-vegetarian diet rich in proteins is provided. 

Necessary laboratory investigations including routine blood examinations like TC, DC, ESR, Biochemical examinations, L.F.T. skin biopsy were carried out besides having photographs of the case at different stages.

1.     Age below 15 years and above 60 years.

2.    Typical distribution of the Psoriatic lesions

Criteria for assessment and diagnosis

1.     Typical distribution of the Psoriatic lesions

2.      Well defined non-indurated, dry erythematous area with silvery layer scaling (30% of body surface involvement)

3.       The candle grease sign.

4.       Positive histopathological findings.

 

 

PLANT PARAMETERS

Capacity  

(Capsules/ Year)

10 million (strips)

15tonne Oil

No. of Shifts  / day

1

Working days / Yr

300

Land Area,  m2

600

Covered Area,  m2

200

MANPOWER

Managerial

1

Skilled

5

Unskilled

10

PLANT & MACHINERY

Wax vessel

 Batch vessel, piping

Drier

Extractor

 Evaporating pans

 Mixer

Oven 

Tube crimping Capsule filling

Strip packing

Oil  Filling, sealing  machine etc.

 

NRDC
National Research Development Corporation, a Government of India Enterprise, is a premier technology transfer Corporation with four decades of experience. It has helped establish over one thousand projects in the small and medium scale sector. The supply of technologies and services to entrepreneurs extend both in the developing and developed countries like USA, Germany, Malaysia , Burma , Nepal, Senegal, Madagascar, Indonesia Philippines, Vietnam, Lanka, Kenya, Brazil, Bangladesh and Egypt.

Services offered by NRDC


National Research Development Corporation
( A Government of India Enterprise )
20-22, Zamroodhpur Community Center
Kailash Colony Extension
New Delhi 110 048. India
Ph: +91-11-26419904, 26417821, 26480767, 26432627
Fax: 011-26231877, 26460506, 26478010
Website:
www.nrdcindia.com
mail:
write2@nrdcindia.com